Longitudinal Variant Monitoringالمراقبة الطولية للمتغيرات

Track variant history, prior classifications, evidence freshness, reviewer decisions, and reclassification watch status across time.تتبع تاريخ المتغير، التصنيفات السابقة، حداثة الأدلة، قرارات المراجعين، وحالة مراقبة إعادة التصنيف عبر الزمن.

0Eventsأحداث

0Classificationsتصنيفات

falseWatch activeمراقبة نشطة

falseFinal reclassنهائي

Run longitudinal monitorشغّل المراقبة الطولية

{"institution":"p209-lab","previous_classification":"VUS","current_draft_classification":"likely_pathogenic","external_report_text":"External report: BRCA1 NM_007294.4 c.68_69del p.Glu23ValfsTer17. Classification: VUS. Report date 2018. Genome build not specified.","evidence":[{"source":"ClinVar live API 2026","summary":"Reviewed pathogenic assertion","confidence":0.82},{"source":"PubMed cached 2018","summary":"Older cohort evidence","confidence":0.7}],"history":[{"timestamp":"2021-04-01","event_type":"prior_review","classification":"VUS","evidence_summary":"Initial VUS from external lab","reviewer_decision":"signed_draft"},{"timestamp":"2024-09-15","event_type":"local_review","classification":"VUS","evidence_summary":"No segregation evidence","reviewer_decision":"keep_vus"}],"case":{"input_type":"longitudinal_monitoring","case_id":"case-p209-demo","phenotype":{"text":"early onset breast cancer family history ovarian cancer","language":"en"},"local_variant_memory_expected":false,"variants":[{"gene":"BRCA1","transcript":"NM_007294.4","hgvs_c":"c.68_69del","hgvs_p":"p.Glu23ValfsTer17"}]}}

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